Refrigerants, antifreezes and cooling liquids include primary refrigerants, secondary refrigerants, and antifreeze additives. A primary refrigerant uses a thermodynamic or adiabatic process (evaporation-condensation cycles) to remove heat and cool a region. A secondary refrigerant, such as antifreeze liquids, provides cooling solely through heat transfer. Antifreeze additives also prevent water-based cooling systems from freezing. Refrigerants, antifreezes, and cooling liquids include refrigerants and refrigeration fluids that are based on halogenated (fluorinated and/or chlorinated) hydrocarbons fluids. They also include glycol-based antifreezes.